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Blended Polymers Open New Avenues in Dosage Forms

Corium's
delivery platforms are based on the company's proprietary Corplex™
hydrogel technology. This new polymer technology, is a versatile medical
polymer system that can be applied to many drug delivery and medical product
applications. The versatility of Corplex™ is that it encompasses the
blending of polymers that are mixed in a fashion unlike most pharmaceutical
products. It has undergone several years of basic research to fully understand
its uniqueness around bioadhesive, water absorption, physical and chemical
properties.

Key Benefits:
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Faster regulatory approvals |
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Elimination of toxicology & safety
concerns |
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Accelerated time to market |
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Cost savings |

We are now taking this blending know-how and polymer chemistry to further
develop a series of products that can be made in the form of liquid (sprays,
film formers), semisolid (gel, creams and ointment-like) and solid (powder,
particles, dry and wet films).
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| Corplex™ Hydrogel Technology |
| Range of Hydrophilic to Hydrophobic Properties |
| Excellent Adhesion to Dry and Wet Surfaces |
| Ability to Formulate Corplex™ Adhesive Properties
to Compliment Your Products' Unique Properties* |
| Extrusion Process Offers Option for Solvent-Free Mixing
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| Range of Wear Time (seconds to hours to days) |
| Enhanced Skin Permeation |
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*ability to work with other adhesive
systems as well.
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